Description

N-(1-Acetyl-4-Piperidinyl)-4-Fluoro-Benzamide is a high-purity, advanced pharmaceutical intermediate characterized by its distinct piperidine-acetyl and fluoro-benzamide structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting specific biological pathways. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology firms, and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates for central nervous system (CNS) disorders, oncology, and inflammation.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its modifiable acetyl-piperidine moiety.
• API Development: Serves as a precursor in the multi-step synthesis of complex target molecules for preclinical and clinical studies.
• Biochemical Tool Compound: Potential use as a probe or inhibitor in biochemical assays to study enzyme or receptor function.
• Custom Synthesis: Starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	N-(1-Acetyl-4-Piperidinyl)-4-Fluoro-Benzamide
CAS No.	283167-06-6
Molecular Formula	C14H17FN2O2
Molecular Weight	264.30 g/mol
Synonyms	4-Fluoro-N-(1-acetylpiperidin-4-yl)benzamide; 1-Acetyl-4-[(4-fluorobenzoyl)amino]piperidine; N-(1-Acetyl-4-piperidyl)-4-fluorobenzamide; 4-Fluoro-N-(1-acetyl-4-piperidinyl)benzamide; 283167-06-6; 4-Fluorobenzoic acid (1-acetyl-4-piperidinyl)amide; UNII-9J7F8C6S4R
EINECS	Contact for details

Quality Control

Our N-(1-Acetyl-4-Piperidinyl)-4-Fluoro-Benzamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.