Description

β-Nicotinamide Adenine Dinucleotide Tetrahydrate, Crystalline, 98+% CAS NO 282730-13-6 is the reduced, coenzyme form of NAD+, a critical redox cofactor in numerous biological energy transfer and metabolic pathways. This high-purity crystalline grade is essential for research and industrial processes requiring a reliable and consistent source of the active electron donor. It is primarily utilized by biotech, pharmaceutical, and diagnostic sectors for enzymatic assays, metabolic studies, and as a key reagent in biocatalysis and fermentation processes.

Application

• Enzymatic Assays & Diagnostic Kits: Serves as an essential co-substrate in dehydrogenase-based assays for clinical diagnostics and biochemical research.
• Biocatalysis & Industrial Enzymology: Used as a cofactor in enzymatic synthesis for the production of chiral intermediates, fine chemicals, and active pharmaceutical ingredients (APIs).
• Cell Culture & Fermentation Media: Employed in specialized mammalian and microbial cell culture systems to support cellular metabolism and improve product yield.
• Metabolic Pathway Research: A fundamental reagent for in vitro studies of glycolysis, the citric acid cycle, and other NADH-dependent metabolic processes.
• Pharmaceutical R&D: Used in drug discovery screens targeting metabolic enzymes and in stability testing of related formulations.
• Nutraceutical & Cosmetic Research: Investigated for its role in cellular energy metabolism and anti-aging applications in advanced research settings.

Basic Information

Product Name	β-Nicotinamide Adenine Dinucleotide Tetrahydrate, Crystalline, 98+%
CAS No.	282730-13-6
Molecular Formula	C21H29N7O14P2 • 4H2O
Molecular Weight	709.45 g/mol (Anhydrous: 637.40 g/mol)
Synonyms	NADH, Tetrahydrate; DPNH; Reduced Nicotinamide Adenine Dinucleotide; β-NADH; Coenzyme I, reduced; Dihydrocodehydrogenase I; Adenine-Nicotinamide Dinucleotide, Reduced; 1,4-Dihydronicotinamide adenine dinucleotide; β-DPNH
EINECS	Contact for details

Quality Control

Our β-Nicotinamide Adenine Dinucleotide Tetrahydrate is manufactured under strict quality management systems. Each batch is tested to ensure it meets the high-purity specification of 98% minimum by HPLC. Certificates of Analysis (COA) are provided, detailing key parameters including assay, identity, and purity profile. We support compliance with cGMP and ISO 9001 standards for research and industrial use.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, keep desiccated under an inert atmosphere. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	10.0% - 13.0% (Theoretical for Tetrahydrate: ~10.2%)
pH (1% Solution)	5.0 - 7.0
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Rotation	Contact for details
Bacterial Endotoxins	< 10 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.