Description

Cyclopentaneacetic Acid, 1-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]- (9Ci) is a specialized Fmoc-protected amino acid derivative, a key building block in modern peptide synthesis. This high-purity intermediate is critical for ensuring the fidelity and efficiency of solid-phase peptide synthesis (SPPS) processes. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the development of novel peptide-based therapeutics, diagnostics, and research tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a protected amino acid derivative for the controlled, sequential assembly of custom peptides.
• Pharmaceutical Research & Development: A crucial intermediate in the synthesis of peptide drug candidates and active pharmaceutical ingredients (APIs).
• Bioconjugation & Labeling: Used to introduce the cyclopentaneacetic acid moiety into peptides for subsequent conjugation with dyes, polymers, or other biomolecules.
• Combinatorial Chemistry Libraries: Serves as a building block for creating diverse libraries of peptide-like compounds for high-throughput screening.
• Academic & Institutional Research: Employed in biochemical and medicinal chemistry studies investigating peptide structure-activity relationships (SAR).
• Production of Peptide Fragments: For generating specific peptide sequences used as antigens, standards, or probes in biological assays.

Basic Information

Product Name	Cyclopentaneacetic Acid, 1-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]- (9Ci)
CAS No.	282524-99-6
Molecular Formula	C22H23NO4
Molecular Weight	365.42 g/mol
Synonyms	1-(Fmoc-amino)cyclopentaneacetic acid; Fmoc-1-Aminocyclopentane-1-acetic acid; 1-[(9H-Fluoren-9-ylmethoxy)carbonylamino]cyclopentane-1-acetic acid; Fmoc-Acpc-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1-aminocyclopentane-1-acetic acid; Nα-Fmoc-1-amino-1-cyclopentanecarboxylic acid (common misnomer); Fmoc-ACPA-OH; Fmoc-1-Amino-1-cyclopentanecarboxylic acid, acetic acid derivative
EINECS	Contact for details

Quality Control

This product is manufactured under strict quality management systems to meet the exacting standards of pharmaceutical and biotech research. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and specific tests for residual solvents and moisture (KF). A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.