Description

Cyclopentanecarboxylic Acid, 2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]- (9Ci) is a specialized Fmoc-protected amino acid derivative, a critical building block in modern synthetic chemistry. Its primary value lies in enabling the precise and efficient synthesis of complex peptides and peptidomimetics, which are essential for pharmaceutical research and development. This high-purity intermediate is indispensable for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require reliable, high-quality reagents for solid-phase peptide synthesis (SPPS) and other sophisticated organic syntheses.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid building block for the automated synthesis of therapeutic peptides and peptide libraries.
• Pharmaceutical Intermediate: Used in the research and development of novel active pharmaceutical ingredients (APIs), particularly for metabolic and neurological targets.
• Peptidomimetic Design: Facilitates the creation of peptide-like compounds with enhanced stability and bioavailability for drug discovery programs.
• Bioconjugation and Labeling: Serves as a precursor for creating labeled peptides or peptide-drug conjugates used in diagnostics and targeted therapies.
• Academic and Industrial Research: A vital reagent in chemical biology and medicinal chemistry laboratories for exploring protein-protein interactions and developing new bioactive molecules.
• Custom Oligomer Synthesis: Employed by CROs and CDMOs for the contract manufacturing of specific peptide sequences for clients.

Basic Information

Item	Detail
Product Name	Cyclopentanecarboxylic Acid, 2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]- (9Ci)
CAS No.	282524-97-4
Molecular Formula	C21H21NO4
Molecular Weight	351.40 g/mol
Synonyms	Fmoc-1-Aminocyclopentane-1-carboxylic Acid; Fmoc-Acp-OH; 1-[(9H-Fluoren-9-ylmethoxy)carbonylamino]cyclopentanecarboxylic Acid; Fmoc-ACPC-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1-aminocyclopentanecarboxylic Acid; 1-(Fmoc-amino)cyclopentanecarboxylic Acid; Nα-Fmoc-1-amino-1-cyclopentanecarboxylic acid
EINECS	Contact for details

Quality Control

Our Cyclopentanecarboxylic Acid, 2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]- (9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, meeting the exacting standards required for pharmaceutical research. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP and REACH guidelines for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and may require storage under an inert atmosphere for long-term stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.