Description

3-(9 H-Fluoren-9-Ylmethoxycarbonylamino)-Hexanoic Acid is a specialized Fmoc-protected amino acid derivative, a crucial building block in modern peptide synthesis. Its primary value lies in enabling the controlled, sequential assembly of complex peptides, particularly those requiring specific side-chain modifications or non-natural amino acid incorporation. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors who are developing novel therapeutic peptides, peptide-based diagnostics, and advanced biomaterials.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled, stepwise elongation of peptide chains on resin supports.
• Peptide Drug Development: Used in the research and production of novel peptide-based pharmaceuticals, including hormone analogs and targeted therapeutics.
• Bioconjugation and Labeling: Facilitates the site-specific attachment of fluorophores, biotin, or other functional groups to peptides for diagnostic and imaging applications.
• Combinatorial Chemistry Libraries: Serves as a building block for generating diverse peptide libraries used in high-throughput screening for drug discovery.
• Non-Natural Amino Acid Incorporation: Enables the synthesis of peptides containing modified or engineered amino acids to enhance stability, activity, or bioavailability.
• Academic and Industrial Research: A fundamental reagent for studying protein-protein interactions, enzyme substrates, and peptide structure-activity relationships.

Basic Information

Item	Detail
Product Name	3-(9 H-Fluoren-9-Ylmethoxycarbonylamino)-Hexanoic Acid
CAS No.	282524-94-1
Molecular Formula	C₂₅H₂₉NO₄
Molecular Weight	407.50 g/mol
Synonyms	Fmoc-6-Ahx-OH; Fmoc-6-Aminohexanoic Acid; N-α-Fmoc-6-aminohexanoic acid; N-(9-Fluorenylmethoxycarbonyl)-6-aminohexanoic acid; 6-[(9H-Fluoren-9-ylmethoxy)carbonylamino]hexanoic acid; Fmoc-Ahx-OH; Fmoc-ε-Ahx-OH; Fmoc-6-Ahx
EINECS	Contact for details

Quality Control

Our 3-(9 H-Fluoren-9-Ylmethoxycarbonylamino)-Hexanoic Acid is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for sensitive applications like peptide synthesis. We provide comprehensive analytical data, including HPLC purity, chiral purity (where applicable), and identity confirmation. Certificates of Analysis (COA) are available for every batch upon request, detailing all relevant specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.