Description

Threo-Pentononitrile, 4,5-Dideoxy-4-Methyl-2,3-o-(1-Methylethylidene)- (9Ci) is a specialized chiral nitrile derivative, serving as a high-value synthetic intermediate in advanced organic synthesis. Its protected diol and nitrile functionalities make it a critical building block for constructing complex molecules with precise stereochemistry. This compound is essential for research and development in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of nucleoside analogs, antiviral agents, and other active pharmaceutical ingredients (APIs).
• Agrochemical Research: Building block for developing new herbicides, fungicides, and insecticides with targeted activity.
• Fine Chemical Synthesis: Used in the preparation of complex natural products, flavors, and fragrances requiring specific stereochemical configurations.
• Academic & R&D Laboratories: A valuable reagent for methodological development in asymmetric synthesis and carbohydrate chemistry.
• Material Science Precursor: Potential intermediate for synthesizing specialized polymers or liquid crystals with unique properties.

Basic Information

Product Name	Threo-Pentononitrile, 4,5-Dideoxy-4-Methyl-2,3-o-(1-Methylethylidene)- (9Ci)
CAS No.	280766-33-8
Molecular Formula	C10H15NO2
Molecular Weight	181.23 g/mol
Synonyms	4,5-Dideoxy-4-methyl-2,3-O-(1-methylethylidene)-D-threo-pentononitrile; 2,3-O-Isopropylidene-4,5-dideoxy-4-methyl-D-threo-pentononitrile; D-threo-Pentononitrile, 4,5-dideoxy-4-methyl-2,3-O-(1-methylethylidene)-; (4R,5R)-4,5-Dideoxy-4-methyl-2,3-O-isopropylidene-D-threo-pentononitrile; 280766-33-8; Isopropylidene-protected threo-pentononitrile derivative
EINECS	Contact for details

Quality Control

Our Threo-Pentononitrile derivative is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as chiral purity, chemical identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of cGMP for pharmaceutical intermediates and ISO standards for laboratory and industrial chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be sensitive to moisture and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.