Description

Tetra-tert-Butyl 2,2',2'',2'''-((((2-(tert-Butoxy)-2-Oxoethyl)Azanediyl)Bis(Ethane-2,1-Diyl))Bis(Azanetriyl))Tetraacetate is a sophisticated, multi-branched organic compound featuring a central nitrogen-based core protected by tert-butyl ester and tert-butyl ether groups. This molecular architecture makes it a valuable intermediate and protecting group reagent in advanced organic synthesis, particularly for peptide and complex molecule construction. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in developing novel therapeutic agents and bioactive compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, especially those requiring protected amine and carboxylic acid functionalities.
• Peptide Synthesis: Serves as a protecting group reagent for amines and carboxyl groups during solid-phase or solution-phase peptide assembly.
• Ligand and Chelator Precursor: Used in the development of polydentate ligands for catalysis or metal ion chelation studies.
• Dendrimer and Polymer Chemistry: Acts as a multifunctional core or branching unit for constructing dendritic macromolecules and specialty polymers.
• Organic Synthesis Research: Employed in methodological studies for constructing complex molecular architectures under mild conditions.
• Bioconjugation Chemistry: Potential use in creating linkers for attaching payloads to antibodies, proteins, or other biomolecules.

Basic Information

Item	Details
Product Name	Tetra-tert-Butyl 2,2',2'',2'''-((((2-(tert-Butoxy)-2-Oxoethyl)Azanediyl)Bis(Ethane-2,1-Diyl))Bis(Azanetriyl))Tetraacetate
CAS No.	280563-33-9
Molecular Formula	C38H72N4O10
Molecular Weight	744.99 g/mol
Synonyms	1,1',1'',1'''-(((2-(2-(2-(2-(tert-Butoxy)-2-oxoethyl)amino)ethyl)amino)ethyl)azanediyl)bis(ethane-2,1-diyl))tetrakis(azanetriyl))tetrakis(2-methylpropan-2-yl) tetraacetate; N1,N1,N14,N14-Tetrakis(2-((tert-butoxycarbonyl)oxy)ethyl)-3,6,9,12-tetraazatetradecanedioic acid tetra-tert-butyl ester; TBTA Ester Derivative; Multifunctional tert-Butyl Ester Amine; Polyamine-based Protecting Group Reagent
EINECS	Contact for details

Quality Control

Our production of Tetra-tert-Butyl 2,2',2'',2'''-((((2-(tert-Butoxy)-2-Oxoethyl)Azanediyl)Bis(Ethane-2,1-Diyl))Bis(Azanetriyl))Tetraacetate adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is characterized using advanced analytical techniques, and a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided. We support cGMP and ISO 9001 compliant manufacturing principles for traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); ensure the container is sealed under an inert atmosphere such as nitrogen or argon after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.