Description

N(1)-(3,5-Bis(Trifluoromethyl)Benzyl)-N( is a high-value fluorinated aromatic intermediate of significant importance in advanced organic synthesis. Its unique structure, featuring a benzyl group with two trifluoromethyl substituents, makes it a critical building block for creating compounds with enhanced metabolic stability, lipophilicity, and bioavailability. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including kinase inhibitors and other targeted therapeutics.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of advanced drug candidates, particularly kinase inhibitors and receptor antagonists.
• Agrochemical Research: Used to develop novel active ingredients for crop protection with improved environmental and metabolic profiles.
• Material Science: Serves as a monomer or building block for specialty polymers and advanced materials with specific fluorinated properties.
• Ligand Synthesis: Employed in the preparation of sophisticated ligands for catalysis and molecular recognition applications.
• Chemical Biology Probes: Utilized to create fluorinated probes for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring the introduction of a bis(trifluoromethyl)benzyl moiety.

Basic Information

Product Name	N(1)-(3,5-Bis(Trifluoromethyl)Benzyl)-N(
CAS No.	279682-92-7
Molecular Formula	C11H7F6N
Molecular Weight	267.17 g/mol
Synonyms	1-[(3,5-Bis(trifluoromethyl)phenyl)methyl]-1H-imidazole; 1-[(3,5-Bis(trifluoromethyl)benzyl)]imidazole; N-[(3,5-Bis(trifluoromethyl)phenyl)methyl]-1H-imidazole; 1H-Imidazole, 1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-; 279682-92-7; 1-(3,5-Bis(trifluoromethyl)benzyl)imidazole; 1-((3,5-Bis(trifluoromethyl)benzyl))-1H-imidazole
EINECS	Contact for details

Quality Control

Our production of N(1)-(3,5-Bis(Trifluoromethyl)Benzyl)-N( adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.