Description

4-Ethoxy-3-Fluorophenylboronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in enabling the formation of carbon-carbon bonds via the Suzuki-Miyaura cross-coupling reaction, a cornerstone methodology for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop new active ingredients and functional organic compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for constructing biaryl and heterobiaryl structures.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides that require specific fluorinated aromatic motifs for enhanced activity and selectivity.
• Material Science Research: Serves as a precursor in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the preparation of sophisticated ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology Probes: Utilized to create tagged molecules and probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Item	Details
Product Name	4-Ethoxy-3-Fluorophenylboronic Acid
CAS No.	279263-10-4
Molecular Formula	C8H10BFO3
Molecular Weight	183.98 g/mol
Synonyms	(4-Ethoxy-3-fluorophenyl)boronic acid; 3-Fluoro-4-ethoxybenzeneboronic acid; 4-Ethoxy-3-fluorobenzeneboronic acid; Boronic acid, B-(4-ethoxy-3-fluorophenyl)-; 279263-10-4; 3-Fluoro-4-ethoxy phenylboronic acid; 4-Ethoxy-3-fluoro phenyl boronic acid
EINECS	Contact for details

Quality Control

Our 4-Ethoxy-3-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistent performance in coupling reactions. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.