Description

3-Fluoro-4-Morpholinophenylboronic Acid is a high-value boronic acid derivative and a key building block in modern synthetic chemistry. Its structure combines a boronic acid functional group with a fluorine-substituted morpholine ring, making it an essential reagent for constructing complex molecules via cross-coupling reactions. This compound is primarily utilized by research scientists and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and advanced materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for forming carbon-carbon bonds between aryl halides and this boronic acid, enabling the synthesis of complex biaryl structures.
• Pharmaceutical Intermediate: Serves as a key building block in the research and development of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides that require specific fluorinated morpholine motifs for enhanced activity.
• Material Science Research: Employed in the development of organic electronic materials, such as ligands for catalysts or components for organic light-emitting diodes (OLEDs).
• Chemical Biology & Probe Development: Useful for synthesizing molecular probes and inhibitors for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-Fluoro-4-Morpholinophenylboronic Acid
CAS No.	279262-09-8
Molecular Formula	C10H13BFNO3
Molecular Weight	225.03 g/mol
Synonyms	(3-Fluoro-4-morpholinophenyl)boronic acid; 4-(3-Fluoro-4-boronophenyl)morpholine; 3-Fluoro-4-morpholinebenzeneboronic acid; B-(3-Fluoro-4-morpholinophenyl)boronic acid; 279262-09-8; 3-Fluoro-4-morpholinobenzene boronic acid; 4-Morpholinophenyl-3-fluoroboronic Acid
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-4-Morpholinophenylboronic Acid is produced and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for demanding research and scale-up applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a dry, cool, and well-ventilated place. This compound is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.