Description

1-Trifluoromethylcyclopropane-1-Carboxylic Acid is a high-value, multifunctional fluorinated building block essential for modern synthetic chemistry. Its unique structure, featuring a cyclopropane ring and a trifluoromethyl group, makes it a critical intermediate for introducing rigidity and lipophilicity into target molecules. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing drug candidates with improved metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Serves as a precursor for specialty polymers and advanced materials with unique surface properties.
• Ligand & Catalyst Development: Employed in the design of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Fluorine Chemistry Research: A valuable substrate for studying novel fluorination reactions and the properties of fluorinated cyclopropanes.
• Peptidomimetics: Incorporated into peptide analogs to modulate their conformation and biological activity.

Basic Information

Product Name	1-Trifluoromethylcyclopropane-1-Carboxylic Acid
CAS No.	277756-46-4
Molecular Formula	C5H5F3O2
Molecular Weight	154.09 g/mol
Synonyms	1-(Trifluoromethyl)cyclopropane-1-carboxylic acid; Cyclopropanecarboxylic acid, 1-(trifluoromethyl)-; 1-Trifluoromethyl-1-cyclopropanecarboxylic acid; α-(Trifluoromethyl)cyclopropanecarboxylic acid; TFCPCA; Trifluoromethylcyclopropanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our 1-Trifluoromethylcyclopropane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.