Description

Ccp Peptide CAS NO 277748-59-1 is a synthetic cyclic citrullinated peptide, a key antigenic target in autoimmune research and diagnostic development. This compound is critical for its high specificity and purity, enabling reliable and reproducible results in sensitive immunological assays. It is primarily utilized by research institutions, diagnostic kit manufacturers, and pharmaceutical companies focused on autoimmune diseases, particularly rheumatoid arthritis.

Application

• Autoimmune Disease Research: As a primary antigen in studies investigating the pathogenesis of rheumatoid arthritis and other citrullination-related autoimmune disorders.
• Diagnostic Assay Development: Serving as the core coating antigen or detection target in the production of ELISA and other immunoassay kits for anti-CCP antibody testing.
• Biomarker Validation: Used as a reference standard to validate and calibrate assays designed to detect anti-citrullinated protein antibodies (ACPAs) in patient sera.
• Therapeutic Target Investigation: Employed in epitope mapping and the development of potential therapeutic agents, including tolerizing vaccines or specific inhibitors.
• Quality Control Reagent: Acting as a positive control and calibrator in the quality assurance processes of clinical diagnostic laboratories.

Basic Information

Product Name	Ccp Peptide
CAS No.	277748-59-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cyclic Citrullinated Peptide; CCP Antigen; Citrullinated Cyclic Peptide; Anti-CCP Peptide; Citrulline-containing Cyclic Peptide; Rheumatoid Arthritis Peptide Antigen; ACPA Antigen; Synthetic Citrullinated Peptide
EINECS	Contact for details

Quality Control

Our Ccp Peptide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and mass spectrometry for identity confirmation, to ensure it meets the exacting standards required for research and diagnostic applications. Certificates of Analysis (COA) with detailed chromatographic data and specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70% (by weight)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in aqueous buffers or DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.