Description

(E)-3-(2-Furyl)-2-(4-Phenyl-1,3-Thiazol-2-Yl)-2-Propenenitrile is a specialized organic compound featuring a unique molecular architecture combining furan, phenylthiazole, and propenenitrile moieties. This structure makes it a valuable advanced intermediate or building block for the synthesis of complex molecules in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients, particularly in medicinal chemistry for drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, especially those targeting neurological disorders or infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science Precursor: Acts as a monomer or precursor for the development of organic semiconductors, nonlinear optical materials, or specialty polymers.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme interactions.
• Organic Synthesis Scaffold: Provides a versatile scaffold for further functionalization in academic and industrial research to create novel chemical libraries.

Basic Information

Item	Details
Product Name	(E)-3-(2-Furyl)-2-(4-Phenyl-1,3-Thiazol-2-Yl)-2-Propenenitrile
CAS No.	277308-31-3
Molecular Formula	C₁₆H₁₀N₂OS
Molecular Weight	278.33 g/mol
Synonyms	(E)-3-(2-Furyl)-2-(4-phenyl-1,3-thiazol-2-yl)acrylonitrile; 2-Propenenitrile, 3-(2-furanyl)-2-(4-phenyl-2-thiazolyl)-, (E)-; (E)-3-(Furan-2-yl)-2-(4-phenylthiazol-2-yl)acrylonitrile; 277308-31-3; (E)-2-(4-Phenylthiazol-2-yl)-3-(furan-2-yl)acrylonitrile; Acrylonitrile derivative (E)-isomer; Furan-thiazole acrylonitrile derivative
EINECS	Contact for details

Quality Control

Our production of (E)-3-(2-Furyl)-2-(4-Phenyl-1,3-Thiazol-2-Yl)-2-Propenenitrile adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.