Description

Trt-D-Phe-Oh Dea CAS NO 273747-93-6 is a protected amino acid derivative, specifically the diethylammonium salt of N-Trityl-D-phenylalanine. This compound is a crucial chiral building block in the synthesis of complex peptides and pharmaceutical intermediates. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate D-phenylalanine residues while protecting the amine functionality.
• Proteomics Research: Employed in biochemical research for studying enzyme-substrate interactions and designing enzyme inhibitors.
• Asymmetric Synthesis: Acts as a chiral auxiliary or starting material in the preparation of enantiomerically pure compounds.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & R&D: A valuable reagent for universities and contract research organizations (CROs) exploring new synthetic methodologies.

Basic Information

Product Name	Trt-D-Phe-Oh Dea
CAS No.	273747-93-6
Molecular Formula	C31H34N2O2
Molecular Weight	466.62 g/mol
Synonyms	N-Trityl-D-phenylalanine Diethylammonium Salt; D-Phenylalanine, N-(triphenylmethyl)-, compd. with N-ethylethanamine (1:1); (R)-2-((Tritylamino)(phenyl)methyl)propanoic acid diethylamine salt; Trt-D-Phe-OH•DEA; Fmoc-D-Phe(Trityl)-OH Diethylamine; D-Phenylalanine, N-trityl-, diethylamine salt
EINECS	Contact for details

Quality Control

Our Trt-D-Phe-Oh Dea is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and cGMP-grade standards for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.