Description

n-Benzyl-2-Fluorophenylglycine is a specialized fluorinated amino acid derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of novel pharmaceuticals and bioactive molecules. It is primarily utilized by research institutions and industrial R&D departments focused on medicinal chemistry, particularly in the synthesis of protease inhibitors and other targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for protease-targeted therapies.
• Medicinal Chemistry Research: Used as a building block for constructing complex molecular libraries in drug discovery programs to explore structure-activity relationships (SAR).
• Peptidomimetics Synthesis: Employed in the design and synthesis of peptidomimetic compounds, where the fluorine atom and benzyl group offer unique steric and electronic properties.
• Asymmetric Synthesis: Serves as a starting material or intermediate in catalytic asymmetric reactions to introduce chirality into target molecules.
• Bioconjugation & Probe Development: Potential use in creating labeled compounds or probes for biochemical and pharmacological studies due to its modifiable functional groups.

Basic Information

Product Name	n-Benzyl-2-Fluorophenylglycine
CAS No.	271583-21-2
Molecular Formula	C₁₅H₁₄FNO₂
Molecular Weight	259.28 g/mol
Synonyms	2-Fluoro-N-(phenylmethyl)benzeneacetamide; N-Benzyl-2-fluorophenylglycine; (2-Fluorophenyl)(phenylmethyl)aminoacetic Acid; Glycine, N-(phenylmethyl)-, N-(2-fluorophenyl)-; 271583-21-2; Bn-2-F-Phe-OH; N-Bn-2-F-Phe
EINECS	Contact for details

Quality Control

Our n-Benzyl-2-Fluorophenylglycine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.