Description

Fmoc-(S)-3-Amino-(6-Phenyl)-5-Hexenoic Acid is a high-purity, non-natural amino acid derivative featuring an Fmoc-protected amine group and a terminal alkene side chain. This compound is a critical building block for the solid-phase peptide synthesis (SPPS) of peptides with unique structural and functional properties. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, peptide therapeutics development, and chemical biology.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the automated synthesis of complex peptide sequences, particularly those requiring side-chain modification.
• Peptide Drug Discovery: Used to incorporate the unique (S)-3-amino-(6-phenyl)-5-hexenoic acid moiety into novel therapeutic peptides targeting various diseases.
• Chemical Biology Probes: Serves as a precursor for synthesizing labeled or tagged peptides used in studying protein-protein interactions and cellular pathways.
• Material Science: Potential monomer for creating specialized polymers or biomaterials with tailored properties via the reactive alkene handle.
• Academic & Industrial Research: Fundamental reagent for methodological development in organic synthesis and peptide chemistry.

Basic Information

Product Name	Fmoc-(S)-3-Amino-(6-Phenyl)-5-Hexenoic Acid
CAS No.	270596-45-7
Molecular Formula	C27H25NO4
Molecular Weight	427.49 g/mol
Synonyms	Fmoc-(S)-3-Amino-6-phenyl-5-hexenoic acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-amino-6-phenyl-5-hexenoic acid; Fmoc-Ahpe(6-Ph)-OH; (S)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-phenylhex-5-enoic acid; Fmoc-3-Amino-6-phenyl-5-hexenoic acid; N-α-Fmoc-(S)-3-amino-6-phenyl-5-hexenoic acid; Fmoc-(S)-3-Ahpe(6-Ph)-OH; Fmoc-S-3-Amino-(6-phenyl)-5-hexenoic Acid
EINECS	Contact for details

Quality Control

Our Fmoc-(S)-3-Amino-(6-Phenyl)-5-Hexenoic Acid is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for sensitive research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity. Certificates of Analysis (COA) detailing all specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.