Description

6-Fluoro-1-Methyl-1,2,3,4-Tetrahydro-Isoquinoline is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which serves as a critical precursor for developing novel pharmacologically active compounds. This specialty intermediate is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and development of new therapeutic agents, particularly within central nervous system (CNS) and oncology research pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel drug candidates, especially in CNS and oncology research.
• Agrochemical Research: Used in the synthesis of new molecules with potential pesticidal or herbicidal activity.
• Material Science: Serves as a building block for advanced organic materials and functionalized polymers.
• Chemical Biology: Employed as a probe or tag in biochemical research due to its fluorinated structure.
• Academic & R&D: Essential for methodological studies in organic chemistry and medicinal chemistry laboratories worldwide.
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule development.

Basic Information

Product Name	6-Fluoro-1-Methyl-1,2,3,4-Tetrahydro-Isoquinoline
CAS No.	269402-42-8
Molecular Formula	C10H12FN
Molecular Weight	165.21 g/mol
Synonyms	1-Methyl-6-fluoro-1,2,3,4-tetrahydroisoquinoline; 6-Fluoro-1-methyl-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-6-fluoro-1-methylisoquinoline; FMTIQ; 6-F-1-Methyl-THIQ; 269402-42-8; 6-Fluoro-1-methyl-THIQ
EINECS	Contact for details

Quality Control

Our 6-Fluoro-1-Methyl-1,2,3,4-Tetrahydro-Isoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.