Description

Boc-(R)-3-Amino-4-(4-Pyridyl)-Butyric Acid is a high-purity, chiral amino acid derivative featuring a tert-butoxycarbonyl (Boc) protecting group and a pyridyl side chain. This compound serves as a critical pharmaceutical intermediate and building block in advanced organic synthesis, particularly for the development of peptide-based therapeutics and enzyme inhibitors. It is essential for research and manufacturing in the pharmaceutical, biotechnology, and fine chemical sectors, where precise stereochemistry and high purity are non-negotiable for successful outcomes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, especially protease inhibitors and other targeted therapies.
• Peptide Synthesis: Used as a protected amino acid building block in solid-phase and solution-phase peptide synthesis (SPPS) to construct complex peptide sequences.
• Chemical Biology Research: Employed in the design and synthesis of chemical probes, activity-based probes, and peptidomimetics for studying biological pathways.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or starting material in catalytic asymmetric reactions to introduce stereogenic centers.
• API Development: Integral to the research and process development stages for new Active Pharmaceutical Ingredients (APIs) requiring this specific molecular scaffold.
• Academic & Industrial R&D: Serves as a valuable reagent for methodological development in organic chemistry and medicinal chemistry laboratories worldwide.

Basic Information

Item	Detail
Product Name	Boc-(R)-3-Amino-4-(4-Pyridyl)-Butyric Acid
CAS No.	269396-68-1
Molecular Formula	C14H20N2O4
Molecular Weight	280.32 g/mol
Synonyms	(R)-3-((tert-Butoxycarbonyl)amino)-4-(pyridin-4-yl)butanoic acid; Boc-D-3-Amino-4-(4-pyridyl)butyric acid; (R)-Boc-3-Amino-4-(4-pyridyl)butyric acid; tert-Butyl (R)-3-amino-4-(pyridin-4-yl)butanoate derivative; (R)-3-(Boc-amino)-4-(4-pyridyl)butyric acid; 4-Pyridinebutanoic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-, (3R)-; BOC-(R)-3-AMINO-4-(4-PYRIDYL)-BUTANOIC ACID
EINECS	Contact for details

Quality Control

Our Boc-(R)-3-Amino-4-(4-Pyridyl)-Butyric Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm enantiomeric excess, ensuring compliance with research and development standards. Certificates of Analysis (COA) documenting identity, purity, and other critical parameters are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.