Description

Fmoc-4-Carboxymethyl-1,2,3,-Tetrahydroquinoxalin-3-One is a sophisticated, high-purity building block specifically designed for advanced organic synthesis and peptide chemistry. This compound is valued for its role as a protected amino acid derivative, enabling the precise construction of complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, peptidomimetics, and other bioactive compounds.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key Fmoc-protected amino acid analog for the sequential assembly of custom peptide sequences.
• Peptidomimetic Drug Discovery: Used to incorporate the tetrahydroquinoxalinone scaffold into drug candidates, a structure known for its potential biological activity.
• Combinatorial Chemistry Libraries: Acts as a versatile intermediate for generating diverse compound libraries for high-throughput screening.
• Medicinal Chemistry Research: Employed in the synthesis of target molecules for studying protein-protein interactions and enzyme inhibition.
• Bioconjugation: The carboxylic acid group allows for coupling to other molecules, such as fluorescent tags or polymers, for creating bioconjugates.
• Academic & Industrial R&D: A critical reagent for fundamental research in organic synthesis and the development of new synthetic methodologies.

Basic Information

Product Name	Fmoc-4-Carboxymethyl-1,2,3,-Tetrahydroquinoxalin-3-One
CAS No.	269078-84-4
Molecular Formula	C26H20N2O5
Molecular Weight	440.45 g/mol
Synonyms	Fmoc-Tic-OH(4-CH2COOH); N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1,2,3,4-tetrahydro-4-(carboxymethyl)-3-oxo-2-quinoxalinecarboxylic Acid; Fmoc-4-(Carboxymethyl)-3-oxo-1,2,3,4-tetrahydroquinoxaline-2-carboxylic Acid; Fmoc-4-Carboxymethyl-DL-Tic-OH; Fmoc-4-CM-Tic-OH; 1,2,3,4-Tetrahydro-4-(carboxymethyl)-3-oxo-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-2-quinoxalinecarboxylic Acid
EINECS	Contact for details

Quality Control

Our Fmoc-4-Carboxymethyl-1,2,3,-Tetrahydroquinoxalin-3-One is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements, including those for GMP-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. For long-term storage, consider storing under an inert atmosphere to maintain stability. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.