Description

(R,S)-Boc-3-Amino-3-(1-Naphthyl)-Propionic Acid is a protected amino acid derivative of significant importance in advanced organic synthesis. This compound serves as a versatile and high-purity building block for the construction of complex peptide mimetics and pharmaceutical intermediates. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery and development, particularly for creating novel bioactive molecules and peptidomimetics.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates, especially in oncology and CNS research.
• Peptidomimetic Synthesis: Used to incorporate a naphthyl-substituted β-amino acid scaffold into peptide chains to enhance stability, lipophilicity, and receptor binding affinity.
• Chemical Biology Probes: Employed in the development of labeled compounds and activity-based probes for studying enzyme mechanisms and protein-protein interactions.
• Asymmetric Synthesis: Serves as a starting material or intermediate in catalytic asymmetric transformations to create enantiomerically enriched compounds.
• Material Science Research: Potential monomer for the synthesis of specialized polymers with unique optical or structural properties.
• Academic & Industrial R&D: Fundamental building block in medicinal chemistry programs for structure-activity relationship (SAR) studies.

Basic Information

Product Name	(R,S)-Boc-3-Amino-3-(1-Naphthyl)-Propionic Acid
CAS No.	268209-95-6
Molecular Formula	C₁₈H₂₁NO₄
Molecular Weight	315.36 g/mol
Synonyms	3-[(tert-Butoxycarbonyl)amino]-3-(1-naphthyl)propanoic Acid; Boc-3-Amino-3-(1-naphthyl)propionic Acid; tert-Butyl (1-carboxy-2-(naphthalen-1-yl)ethyl)carbamate; (±)-Boc-β-(1-Naphthyl)-β-alanine; N-Boc-3-amino-3-(1-naphthyl)propanoic acid; N-(tert-Butoxycarbonyl)-3-amino-3-(1-naphthyl)propionic Acid; 3-(Boc-amino)-3-(1-naphthyl)propionic Acid
EINECS	Contact for details

Quality Control

Our (R,S)-Boc-3-Amino-3-(1-Naphthyl)-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and spectroscopic identification (NMR, IR, MS), to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Racemic mixture (R,S)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.