Description

Benzenepropanenitrile, 2-Chloro-B-Oxo-3-(Trifluoromethyl)- (CAS 267881-04-9) is a high-value, multi-functional chemical intermediate characterized by its unique trifluoromethyl and cyano groups. This compound is essential for introducing specific structural motifs that enhance the biological activity and metabolic stability of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing complex molecules with potential therapeutic applications, particularly in developing anti-inflammatory, antiviral, or central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve efficacy and environmental profile.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, or organic electronic materials that require specific fluorine-containing aromatic units.
• Organic Synthesis Reagent: Employed in academic and industrial R&D labs for constructing complex heterocycles and other fine chemicals via reactions involving its ketone and nitrile functionalities.

Basic Information

Product Name	Benzenepropanenitrile, 2-Chloro-B-Oxo-3-(Trifluoromethyl)-
CAS No.	267881-04-9
Molecular Formula	C10H5ClF3NO
Molecular Weight	247.60 g/mol
Synonyms	2-Chloro-3-(trifluoromethyl)benzoylacetonitrile; 3-Oxo-2-[2-chloro-3-(trifluoromethyl)phenyl]propanenitrile; 2-Chloro-β-oxo-3-(trifluoromethyl)benzenepropanenitrile; 1-(2-Chloro-3-(trifluoromethyl)phenyl)-2-cyanoethan-1-one; α-Chloro-β-oxo-3'-(trifluoromethyl)benzenepropanenitrile; 2-Chloro-3-(trifluoromethyl)phenacyl cyanide; 2-Chloro-3-trifluoromethylbenzoyl methyl cyanide
EINECS	Contact for details

Quality Control

Our Benzenepropanenitrile, 2-Chloro-B-Oxo-3-(Trifluoromethyl)- is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP or research-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.