Description

3-(4-Bromo-2-Fluorophenyl)-3-Oxopropanenitrile is a versatile and high-value organic intermediate featuring a bromo-fluorophenyl ketone nitrile structure. This compound is critical for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its unique halogenated aromatic core enables precise structural modifications. It is primarily sought after by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), advanced materials, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and pesticides, leveraging the bioactivity of its halogenated aromatic system.
• Material Science Research: Serves as a precursor for the development of organic electronic materials, liquid crystals, and photoactive compounds.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of molecular probes and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	3-(4-Bromo-2-Fluorophenyl)-3-Oxopropanenitrile
CAS No.	267880-92-2
Molecular Formula	C9H5BrFNO
Molecular Weight	242.04 g/mol
Synonyms	4-Bromo-2-fluorobenzoylacetonitrile; 3-Oxo-3-(4-bromo-2-fluorophenyl)propanenitrile; 1-(4-Bromo-2-fluorophenyl)-1,3-butanedione-3-carbonitrile; (4-Bromo-2-fluorobenzoyl)acetonitrile; 3-(4-Bromo-2-fluorobenzoyl)propionitrile; 4'-Bromo-2'-fluorobenzoylacetonitrile; β-Oxo-4-bromo-2-fluorobenzene propanenitrile
EINECS	Contact for details

Quality Control

Our 3-(4-Bromo-2-Fluorophenyl)-3-Oxopropanenitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP and ISO standards for pharmaceutical and industrial applications, ensuring reliable supply and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.