Description

3,4,5-Triethoxybenzoylacetonitrile is a versatile synthetic intermediate characterized by its unique aromatic substitution pattern and reactive nitrile functionality. This compound matters for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical and advanced material research. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing heterocyclic compounds and functionalized aromatic systems.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with tri-substituted benzene cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators that require specific aromatic ether patterns.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport molecules or photoactive compounds.
• Chemical Biology Probes: Useful for constructing molecular probes and tags due to the reactivity of the nitrile and ketone groups.
• Fine Chemical Production: Acts as a building block for dyes, pigments, and other performance chemicals requiring a 3,4,5-triethoxyphenyl moiety.

Basic Information

Product Name	3,4,5-Triethoxybenzoylacetonitrile
CAS No.	267880-91-1
Molecular Formula	C15H19NO4
Molecular Weight	277.32 g/mol
Synonyms	1-(3,4,5-Triethoxyphenyl)-2-cyanoethanone; 2-Cyano-1-(3,4,5-triethoxyphenyl)ethanone; 3,4,5-Triethoxybenzoyl methyl cyanide; (3,4,5-Triethoxybenzoyl)acetonitrile; Acetonitrile, (3,4,5-triethoxybenzoyl)-; Ethanone, 2-cyano-1-(3,4,5-triethoxyphenyl)-
EINECS	Contact for details

Quality Control

Our 3,4,5-Triethoxybenzoylacetonitrile is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation by atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.