Description

2,2-Difluoro-2-Pyridin-2-Ylethanamine is a specialized fluorinated pyridine derivative, a high-value building block in advanced organic synthesis. Its unique structure, featuring a difluoroethylamine side chain on a pyridine ring, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the introduction of fluorine atoms can enhance biological activity, stability, and metabolic profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized nitrogen-containing ligands used in transition metal catalysis for asymmetric synthesis.
• Material Science Research: Employed in the development of fluorinated organic materials, including liquid crystals and functional polymers, where its structure can influence electronic and physical properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways due to its potential as a bioisostere.

Basic Information

Product Name	2,2-Difluoro-2-Pyridin-2-Ylethanamine
CAS No.	267825-68-3
Molecular Formula	C7H8F2N2
Molecular Weight	158.15 g/mol
Synonyms	2-(2,2-Difluoroethyl)pyridine; 2-Pyridineethanamine, 2,2-difluoro-; 2,2-Difluoro-2-(2-pyridinyl)ethanamine; 2-(2,2-Difluoroethyl)pyridinamine; 2,2-Difluoro-2-(pyridin-2-yl)ethan-1-amine; Pyridine, 2-(2,2-difluoroethyl)-; 2-(2,2-Difluoroethyl)pyridine amine
EINECS	Contact for details

Quality Control

Our 2,2-Difluoro-2-Pyridin-2-Ylethanamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong alkalis.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.