Description

Myoseverin is a potent and selective small molecule inhibitor of the protein Cdc2-like kinase (Clk) family, identified by the CAS registry number 267402-71-1. This compound is valued for its critical role in modulating pre-mRNA splicing, making it a powerful research tool for studying cellular differentiation, proliferation, and disease mechanisms. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life sciences sectors for drug discovery and advanced biochemical studies.

Application

• Biochemical Research: A key tool for investigating the mechanisms of pre-mRNA splicing and the biological functions of Clk kinases.
• Drug Discovery & Development: Serves as a reference standard and lead compound in oncology and antiviral research programs targeting splicing regulation.
• Cell Biology Studies: Used to study cell cycle control, differentiation, and apoptosis in various in vitro model systems.
• Academic Research: Employed in university and institutional labs for fundamental research into gene expression and signal transduction pathways.
• Pharmaceutical Intermediates: Can be utilized in the synthesis of more complex molecules for therapeutic evaluation.

Basic Information

Product Name	Myoseverin
CAS No.	267402-71-1
Molecular Formula	C₂₀H₁₈N₄O₃
Molecular Weight	362.38 g/mol
Synonyms	Myoseverin; 2,6-Diamino-8-phenylpurine; 6-Amino-2-[(phenylamino)methyl]-3H-purine-2,8-diol; 8-Phenyl-2,6-diaminopurine; Clk Inhibitor; Splicing Inhibitor Myoseverin; NSC 15677
EINECS	Contact for details

Quality Control

Our Myoseverin is produced under strict quality management systems to ensure high purity and batch-to-batch consistency for research applications. Each lot is accompanied by comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) are available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to yellow solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.