Description

Potassium 2,6-Difluorophenyltrifluoroborate is an organoboron reagent, specifically an aryltrifluoroborate salt, valued for its stability and utility in advanced synthetic chemistry. This compound serves as a crucial coupling partner in transition metal-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura reaction, enabling the efficient construction of complex biaryl structures. It is primarily sought by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and materials science industries for the synthesis of active ingredients and novel organic molecules. Its handling requires attention to its moisture-sensitive nature to maintain reactivity and purity.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) containing difluorophenyl motifs, often found in drug candidates for various therapeutic areas.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the introduction of the 2,6-difluorophenyl group is required for biological activity.
• Suzuki-Miyaura Cross-Coupling: Acts as a stable, air- and moisture-tolerant aryl donor in palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Materials Science Research: Employed in the development of organic electronic materials, ligands for catalysis, and novel polymers.
• Chemical Library Development: A valuable reagent for medicinal and combinatorial chemists constructing diverse compound libraries for high-throughput screening.
• Academic & Industrial R&D: Fundamental research tool in organic synthesis methodologies and catalyst development.

Basic Information

Product Name	Potassium 2,6-Difluorophenyltrifluoroborate
CAS No.	267006-25-7
Molecular Formula	C6H3BF5K
Molecular Weight	219.99 g/mol
Synonyms	Potassium (2,6-Difluorophenyl)trifluoroborate; 2,6-Difluorophenyltrifluoroboronic Acid Potassium Salt; Potassium 2,6-Difluorophenyl-Trifluoroboronate; (2,6-Difluorophenyl)trifluoroborate Potassium Salt; 2,6-Difluorobenzene trifluoroborate potassium salt; ArBF3K (2,6-DiF); Potassium 2,6-Difluorophenyl-BF3
EINECS	Contact for details

Quality Control

Our Potassium 2,6-Difluorophenyltrifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹⁹F, ¹¹B), HPLC for purity assessment, and KF titration for moisture content, to ensure compliance with stringent specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) and desiccated for long-term storage. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
¹⁹F NMR Purity	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.