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Potassium 3-Fluorophenyltrifluoroborate CAS NO 267006-24-6


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CAS No.:267006-24-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Potassium 3-Fluorophenyltrifluoroborate is an organoboron reagent widely used as a key building block in modern synthetic chemistry. Its primary value lies in enabling efficient and selective cross-coupling reactions, such as the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-purity intermediates for drug discovery and specialty chemical synthesis.

Application

  • Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biaryl structures.
  • Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require specific fluorinated aromatic components.
  • Material Science: Serves as a precursor for creating novel organic electronic materials, liquid crystals, and polymers with tailored properties.
  • Suzuki-Miyaura Cross-Coupling: The primary application, acting as a stable, air- and moisture-tolerant boronate source for palladium-catalyzed carbon-carbon bond formation.
  • Chemical Research & Development: A valuable tool in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries.
  • Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands and organometallic catalysts used in asymmetric synthesis.

Basic Information

Product Name Potassium 3-Fluorophenyltrifluoroborate
CAS No. 267006-24-6
Molecular Formula C6H4BF4K
Molecular Weight 209.99 g/mol
Synonyms Potassium (3-Fluorophenyl)trifluoroborate; 3-Fluorophenyltrifluoroborate Potassium Salt; Potassium Trifluoro(3-fluorophenyl)borate; 3-Fluorophenylboronic Acid Potassium Trifluoroborate Salt; (3-Fluorophenyl)trifluoroboronic Acid Potassium Salt; 3-Fluorophenyl-BF3K; 3-FC6H4BF3K
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Quality Control

Our Potassium 3-Fluorophenyltrifluoroborate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR (1H, 13C, 19F, 11B), HPLC for purity assessment, and KF titration for moisture content, to ensure it meets the high standards required for sensitive cross-coupling reactions. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity. Keep away from strong acids and strong oxidizing agents.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
NMR Purity (19F) ≥ 95.0%
Solubility Soluble in water, methanol, DMF; slightly soluble in THF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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