Description

β-Catenin Peptide is a high-purity synthetic peptide fragment corresponding to a specific sequence of the β-catenin protein, a key component of the Wnt signaling pathway and cell adhesion complexes. This compound is essential for fundamental life science research, enabling the study of protein-protein interactions, signaling cascades, and cellular processes related to development and disease. It is primarily utilized by researchers and scientists in pharmaceutical R&D, academic institutions, and biotechnology companies for applications such as antibody production, assay development, and mechanistic studies in oncology and regenerative medicine.

Application

• Biochemical Research: Used as a critical reagent for studying the structure, function, and interactions of the β-catenin protein within the Wnt/β-catenin signaling pathway.
• Antibody Production & Validation: Serves as a specific immunogen for generating polyclonal or monoclonal antibodies, or as a standard/blocking peptide in immunoassays like ELISA and Western Blot.
• Drug Discovery & Screening: Employed in high-throughput screening (HTS) assays and in vitro studies to identify and characterize novel inhibitors or modulators of β-catenin-related protein interactions.
• Cell Signaling Studies: Utilized in pull-down assays, co-immunoprecipitation (Co-IP), and other techniques to investigate binding partners and downstream effects in cancer research (e.g., colorectal, hepatocellular carcinoma).
• Diagnostic Development: Acts as a reference material or coating antigen in the development of diagnostic kits targeting β-catenin or associated biomarkers.
• Protein Engineering: Provides a defined sequence for structural biology studies, including X-ray crystallography or NMR, to understand molecular binding sites.

Basic Information

Product Name	β-Catenin Peptide
CAS No.	265669-37-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	β-Catenin fragment; β-Catenin derived peptide; CTNNB1 peptide; Catenin β-1 peptide; β-Catenin peptide; Wnt signaling pathway peptide; Cadherin-associated protein peptide; Armadillo repeat protein peptide
EINECS	Contact for details

Quality Control

Our β-Catenin Peptide is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and mass spectrometry (MS) for identity confirmation, to ensure it meets the high standards required for research applications. Certificates of Analysis (COA) detailing purity, sequence, and analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to keep the peptide lyophilized and desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70% (by weight)
Solubility	Soluble in water or appropriate aqueous buffers
Single Peak on HPLC	Present
Water Content (K.F.)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.