Description

Ethyl 3,3,3-Trifluoro-2-(Hydroxyimino)Propanoate is a high-value fluorinated building block characterized by its reactive oxime ester and trifluoromethyl functionalities. This compound is essential for the synthesis of advanced agrochemicals and pharmaceuticals, where its unique structure enables the introduction of the metabolically stable trifluoromethyl group. It is primarily sought after by research and development chemists in the fine chemical, agrochemical, and pharmaceutical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) containing trifluoromethyl groups, which enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Critical building block for developing next-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Advanced Material Research: Used in the development of specialty polymers and functional materials that require fluorinated components for specific chemical resistance or surface properties.
• Organic Synthesis Reagent: Serves as a versatile reagent for introducing the -CF3 moiety and the reactive oxime ester group into complex molecular architectures in academic and industrial R&D.
• Ligand and Catalyst Development: Employed in the preparation of novel ligands and catalysts for asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	Ethyl 3,3,3-Trifluoro-2-(Hydroxyimino)Propanoate
CAS No.	263750-66-9
Molecular Formula	C5H6F3NO3
Molecular Weight	185.10 g/mol
Synonyms	Ethyl 3,3,3-Trifluoro-2-(hydroxyimino)propionate; 2-(Hydroxyimino)-3,3,3-trifluoropropanoic Acid Ethyl Ester; 3,3,3-Trifluoro-2-(hydroxyimino)propionic Acid Ethyl Ester; Ethyl 3,3,3-Trifluoro-2-oximino-propanoate; TFHP-OEt; Ethyl Trifluoropyruvate Oxime; Ethyl 2-(Hydroxyimino)-3,3,3-trifluoropropanoate
EINECS	Contact for details

Quality Control

Our production of Ethyl 3,3,3-Trifluoro-2-(Hydroxyimino)Propanoate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.