Description

2-(Boc-Amino)Ethoxylbenzonitrile is a high-purity, protected amino acid derivative and a crucial Boc-protected synthetic intermediate. Its primary value lies in enabling the controlled synthesis of complex molecules, particularly in peptide chemistry and pharmaceutical research, where protecting group strategies are essential. This compound is specifically needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for constructing novel active pharmaceutical ingredients (APIs) and advanced organic materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Serves as a protected amino acid derivative for solid-phase and solution-phase peptide synthesis.
• Organic Synthesis: Versatile intermediate for constructing complex heterocyclic compounds and functionalized aromatic systems.
• Protecting Group Strategy: Utilized in multi-step syntheses where the Boc (tert-butoxycarbonyl) group provides temporary protection for amine functionalities.
• Bioconjugation: Potential use in the development of linker molecules for antibody-drug conjugates (ADCs) and other bioconjugates.
• Material Science Research: Intermediate in the synthesis of specialty polymers and advanced organic materials with specific functional properties.

Basic Information

Product Name	2-(Boc-Amino)Ethoxylbenzonitrile
CAS No.	263409-80-9
Molecular Formula	C14H18N2O3
Molecular Weight	262.31 g/mol
Synonyms	2-[(tert-Butoxycarbonyl)amino]ethoxybenzonitrile; 2-(2-((tert-Butoxycarbonyl)amino)ethoxy)benzonitrile; Benzonitrile, 2-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-; 2-(Boc-aminoethoxy)benzonitrile; N-Boc-2-aminoethoxybenzonitrile; tert-Butyl N-[2-(2-cyanophenoxy)ethyl]carbamate; Boc-AEEA-CN derivative
EINECS	Contact for details

Quality Control

Our 2-(Boc-Amino)Ethoxylbenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP, ICH Q7, and other relevant pharmaceutical guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.