Description

D-2-Cyanophenylalanine is a non-natural, chiral amino acid derivative featuring a cyano group on the phenyl ring. This compound is a valuable synthetic building block and a key intermediate in the development of pharmaceuticals and biochemical tools. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for applications in drug discovery, peptide engineering, and as a precursor for more complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for protease inhibitors and other targeted therapies.
• Peptide Research & Modification: Used to incorporate non-natural amino acids into peptides to study structure-activity relationships, enhance metabolic stability, or introduce novel functionalities.
• Chemical Biology Probes: Serves as a precursor for developing activity-based probes and other tools to study enzyme function and biological pathways.
• Ligand Synthesis for Catalysis: Employed in the preparation of chiral ligands for asymmetric catalysis, aiding in the synthesis of enantiomerically pure compounds.
• Academic & Industrial R&D: A fundamental reagent for organic synthesis and medicinal chemistry research in both university laboratories and industrial R&D departments.

Basic Information

Product Name	D-2-Cyanophenylalanine
CAS No.	263396-41-4
Molecular Formula	C₁₀H₁₀N₂O₂
Molecular Weight	190.20 g/mol
Synonyms	(R)-2-Amino-3-(2-cyanophenyl)propanoic acid; D-2-Cyano-Phe; D-2-CN-Phe; D-β-(2-Cyanophenyl)alanine; (R)-2-Cyanophenylalanine; H-D-2-CN-Phe-OH; D-2-Cyanophenylalanine; D-2-Cyano-phenylalanine
EINECS	Contact for details

Quality Control

Our D-2-Cyanophenylalanine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed HPLC, NMR, and optical rotation data are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee (D-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.