Description

2-Bromo-3-Methylbenzonitrile is a versatile halogenated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both bromine and nitrile functional groups, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for applications such as Suzuki-Miyaura cross-coupling reactions and the synthesis of novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated aromatic core.
• Material Science Research: Serves as a precursor for functionalized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Sonogashira couplings to form biaryl and other complex structures.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for metal catalysis and organocatalysts.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological systems and enzyme inhibition.

Basic Information

Product Name	2-Bromo-3-Methylbenzonitrile
CAS No.	263159-64-4
Molecular Formula	C8H6BrN
Molecular Weight	196.04 g/mol
Synonyms	3-Methyl-2-bromobenzonitrile; 2-Bromo-3-methylbenzonitrile; 2-Bromo-m-tolunitrile; Benzonitrile, 2-bromo-3-methyl-; 3-Methyl-2-bromobenzonitrile; 2-Bromo-3-tolunitrile; o-Bromo-m-tolunitrile
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Methylbenzonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and our quality control protocols are designed to meet the stringent requirements of research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.