Description

Carbamic Acid, [(1R)-1-(Hydroxymethyl)-1-Methyl-2-Propenyl]-, 1,1- is a specialized chiral carbamate derivative, a key building block in advanced organic synthesis. Its value lies in its unique stereochemistry and functional groups, which enable the construction of complex molecular architectures with high precision. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating active pharmaceutical ingredients (APIs) and novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, especially in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced, enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the development of new chiral catalysts for stereoselective reactions.
• Peptidomimetics & Prodrug Design: Its carbamate and hydroxymethyl groups make it valuable for constructing peptide backbones and designing prodrugs with enhanced bioavailability.
• Material Science Monomer: Potential use as a specialty monomer for creating polymers with specific chiral or functional properties.

Basic Information

Product Name	Carbamic Acid, [(1R)-1-(Hydroxymethyl)-1-Methyl-2-Propenyl]-, 1,1-
CAS No.	263016-97-3
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	(R)-1-(Hydroxymethyl)-1-methylallyl carbamate; (1R)-1-(Hydroxymethyl)-1-methylprop-2-en-1-yl carbamate; (R)-1-Methyl-1-(hydroxymethyl)allyl carbamate; Chiral tert-allyl carbamate derivative; (R)-HMPA carbamate; (R)-1-Methyl-1-(hydroxymethyl)-2-propenyl carbamate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high chiral purity. Quality is verified through comprehensive analytical techniques including HPLC, chiral GC/HPLC, and NMR. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, enantiomeric excess, and impurity profiles to meet your R&D and scale-up requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.