Description

2,3,4,5-Tetrafluorophenylacetic Acid is a high-value fluorinated aromatic building block essential for advanced organic synthesis. Its unique perfluorinated phenylacetic acid structure makes it a critical intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where fluorine substitution enhances biological activity and stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Polymer Chemistry: Acts as a monomer or modifier for creating specialty polymers with enhanced chemical resistance and thermal stability.
• Organic Synthesis Reagent: Employed in coupling reactions (e.g., Suzuki, Heck) and as a precursor for other fluorinated synthons in complex molecule assembly.
• Material Science Research: Utilized in developing novel organic electronic materials and advanced coatings.

Basic Information

Product Name	2,3,4,5-Tetrafluorophenylacetic Acid
CAS No.	261952-21-0
Molecular Formula	C8H4F4O2
Molecular Weight	208.11 g/mol
Synonyms	(2,3,4,5-Tetrafluorophenyl)acetic Acid; 2-(2,3,4,5-Tetrafluorophenyl)acetic Acid; Tetrafluorophenylacetic Acid; Perfluorophenylacetic Acid (specific isomer); α-(2,3,4,5-Tetrafluorophenyl)acetic Acid; 2,3,4,5-Tetrafluorobenzeneacetic Acid; TFPAA; 261952-21-0
EINECS	Contact for details

Quality Control

Our 2,3,4,5-Tetrafluorophenylacetic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.