Description

3-Methyl-5-(Trifluoromethyl)Benzamide is a high-purity, specialized benzamide derivative featuring a trifluoromethyl group, a key structural motif valued for its ability to modulate the physicochemical properties of advanced molecules. This compound serves as a critical pharmaceutical intermediate and building block in the synthesis of active ingredients for agrochemicals and life sciences. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate fluorine-containing aromatic systems into their target compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used as a building block for developing advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Employed in organometallic chemistry and catalysis research to create novel ligands for transition metal complexes.
• Material Science Research: Serves as a monomer or precursor for synthesizing specialty polymers and advanced organic materials with specific electronic or surface properties.
• Fluorine Chemistry Studies: An important compound for academic and industrial research focused on the synthesis and reactivity of fluorinated aromatic systems.
• Custom Synthesis and Contract Manufacturing: A starting material for custom synthesis services catering to the needs of biotechnology and fine chemical companies.

Basic Information

Product Name	3-Methyl-5-(Trifluoromethyl)Benzamide
CAS No.	261951-98-8
Molecular Formula	C9H8F3NO
Molecular Weight	203.16 g/mol
Synonyms	3-Methyl-5-(trifluoromethyl)benzamide; 5-(Trifluoromethyl)-m-toluamide; m-Toluamide, 5-(trifluoromethyl)-; 3-Methyl-5-trifluoromethylbenzamide; Benzamide, 3-methyl-5-(trifluoromethyl)-; 261951-98-8; 3-Methyl-α,α,α-trifluoro-m-toluamide
EINECS	Contact for details

Quality Control

Our 3-Methyl-5-(Trifluoromethyl)Benzamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical parameters such as assay purity, impurity profile, and physical characteristics.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.