Description

4-(Bromomethyl)-3-Methylphenyl Trifluoromethyl Ether, also known as 1-(Bromomethyl)-2-Methyl-4-(Trifluoromethoxy)Benzene, is a versatile and high-value aromatic building block featuring both a reactive bromomethyl group and a stable trifluoromethoxy substituent. This compound is essential for advanced organic synthesis, particularly in the development of pharmaceuticals and agrochemicals where the introduction of fluorine-containing motifs is critical for enhancing metabolic stability and bioactivity. Researchers and process chemists in fine chemical, pharmaceutical R&D, and material science industries rely on this high-purity intermediate for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring trifluoromethoxy-phenyl motifs for improved drug-like properties.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the fluorine and bromine functionalities contribute to efficacy and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Cross-Coupling Reactions: The bromomethyl group acts as an excellent handle for further functionalization via Suzuki, Heck, or other palladium-catalyzed cross-coupling reactions.
• Ligand & Catalyst Development: Utilized in the preparation of specialized phosphine or nitrogen-based ligands for asymmetric catalysis.
• Polymer & Resin Modifier: Incorporated into polymer chains to introduce fluorine, altering physical properties like solubility, thermal stability, and surface energy.

Basic Information

Product Name	4-(Bromomethyl)-3-Methylphenyl Trifluoromethyl Ether
CAS No.	261951-95-5
Molecular Formula	C10H10BrF3O
Molecular Weight	283.09 g/mol
Synonyms	1-(Bromomethyl)-2-Methyl-4-(Trifluoromethoxy)Benzene; 3-Methyl-4-(bromomethyl)phenyl Trifluoromethyl Ether; 4-(Bromomethyl)-3-Methyl-1-(Trifluoromethoxy)benzene; 2-Methyl-4-(trifluoromethoxy)benzyl Bromide; α-Bromo-2-methyl-4-(trifluoromethoxy)toluene; 1-Bromomethyl-2-methyl-4-trifluoromethoxybenzene; Benzene, 1-(bromomethyl)-2-methyl-4-(trifluoromethoxy)-
EINECS	Contact for details

Quality Control

Our 4-(Bromomethyl)-3-Methylphenyl Trifluoromethyl Ether is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and consistency, meeting the stringent requirements for research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.