Description

2-Methyl-4-(Trifluoromethoxy)Benzonitrile is a versatile aromatic nitrile derivative featuring a trifluoromethoxy substituent. This compound serves as a critical advanced pharmaceutical intermediate (API) and a valuable building block in modern synthetic chemistry. It is primarily utilized by pharmaceutical R&D and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and inflammation.
• Agrochemical Synthesis: Used as a precursor in the development of new-generation herbicides and insecticides, leveraging the stability imparted by the trifluoromethoxy group.
• Liquid Crystal Materials: Serves as a building block for high-performance liquid crystal compounds used in display technologies.
• Organic Electronics: Employed in the research and development of organic semiconductors and electron-transport materials.
• Fluorine Chemistry Research: An important substrate for studying the effects of fluorine and trifluoromethoxy groups on aromatic systems in medicinal and materials chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	2-Methyl-4-(Trifluoromethoxy)Benzonitrile
CAS No.	261951-92-2
Molecular Formula	C9H6F3NO
Molecular Weight	201.15 g/mol
Synonyms	4-(Trifluoromethoxy)-2-methylbenzonitrile; 2-Methyl-4-(trifluoromethoxy)benzonitrile; 2-Methyl-α,α,α-trifluoro-p-anisonitrile; Benzonitrile, 2-methyl-4-(trifluoromethoxy)-; 4-Cyano-3-methylphenyl trifluoromethyl ether; 3-Methyl-4-cyanophenyl trifluoromethyl ether
EINECS	Contact for details

Quality Control

Our 2-Methyl-4-(Trifluoromethoxy)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles where applicable for pharmaceutical-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.