Description

1-Bromo-3-Fluoro-2-(Trifluoromethyl)Benzene is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring bromine, fluorine, and a trifluoromethyl group on the benzene ring, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of fluorinated drug candidates targeting CNS disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved performance in electronic displays.
• Polymer & Material Science: Employed as a monomer or modifier to introduce fluorine into polymers, enhancing properties like chemical resistance, thermal stability, and low surface energy for specialty coatings.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to create complex biaryl and conjugated systems.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating novel fluorinated compounds for various applications.

Basic Information

Product Name	1-Bromo-3-Fluoro-2-(Trifluoromethyl)Benzene
CAS No.	261951-85-3
Molecular Formula	C7H3BrF4
Molecular Weight	243.00 g/mol
Synonyms	2-Bromo-6-Fluorobenzotrifluoride; 3-Fluoro-2-(trifluoromethyl)bromobenzene; 1-Bromo-3-fluoro-2-(trifluoromethyl)benzene; 2-(Trifluoromethyl)-3-fluorobromobenzene; Benzene, 1-bromo-3-fluoro-2-(trifluoromethyl)-; 261951-85-3
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Fluoro-2-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures reliability for your critical synthesis and development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.