Description

2,6-Difluoro-3-Methylphenylacetic Acid is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research and development chemists and production units engaged in creating novel active ingredients, where the introduction of fluorine atoms and the acetic acid moiety are critical for modulating biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutics where fluorination enhances metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a key building block for developing advanced herbicides, fungicides, and insecticides, leveraging the fluorine atoms to improve pesticidal activity and environmental profile.
• Liquid Crystal Materials: Used in the research and production of fluorinated liquid crystals for display technologies, where its structure contributes to desired nematic phases and stability.
• Organic Electronic Materials: Acts as a monomer or intermediate in the synthesis of novel organic semiconductors and electroactive polymers.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reactions, catalytic processes, and the development of novel fluorinated compounds.
• Custom Synthesis & Contract Manufacturing: A specified intermediate for custom synthesis projects requiring high-purity, structurally defined fluorinated aromatics.

Basic Information

Product Name	2,6-Difluoro-3-Methylphenylacetic Acid
CAS No.	261943-97-9
Molecular Formula	C9H8F2O2
Molecular Weight	186.16 g/mol
Synonyms	2,6-Difluoro-3-methylbenzeneacetic acid; (2,6-Difluoro-3-methylphenyl)acetic acid; 3-Methyl-2,6-difluorophenylacetic acid; α-(2,6-Difluoro-3-methylphenyl)acetic acid; 2-(2,6-Difluoro-3-methylphenyl)acetic acid; DFMPAA; 261943-97-9 (CAS)
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-3-Methylphenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure it meets the high-purity standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%; Any single unknown impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.