Description

5-Chloro-2-(Trifluoromethyl)Phenylacetonitrile is a versatile and high-value fluorinated aromatic nitrile building block, essential for advanced organic synthesis. Its molecular structure, featuring both chloro and trifluoromethyl substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated components in electronic display technologies and organic light-emitting diodes (OLEDs).
• Functional Material Research: Employed in academic and industrial R&D to create novel polymers, ligands for catalysis, and advanced organic frameworks with specific electronic characteristics.
• Custom Synthesis & Contract Manufacturing: A fundamental substrate for custom chemical synthesis services, enabling the production of bespoke compounds for client-specific projects.

Basic Information

Product Name	5-Chloro-2-(Trifluoromethyl)Phenylacetonitrile
CAS No.	261763-26-2
Molecular Formula	C9H5ClF3N
Molecular Weight	219.59 g/mol
Synonyms	2-(5-Chloro-2-(trifluoromethyl)phenyl)acetonitrile; (5-Chloro-2-(trifluoromethyl)phenyl)acetonitrile; α-Chloro-α,α,α-trifluoro-o-tolunitrile (related); 2-Chloro-α,α,α-trifluoro-p-toluonitrile (isomer); 5-Chloro-α,α,α-trifluoro-o-toluonitrile; Benzeneacetonitrile, 5-chloro-2-(trifluoromethyl)-; 261763-26-2; 5-Chloro-2-trifluoromethylphenylacetonitrile
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-(Trifluoromethyl)Phenylacetonitrile is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.