Description

5-Chloro-2-(Trifluoromethyl)Phenylacetic Acid is a versatile and high-value fluorinated aromatic building block. This compound is essential for the synthesis of advanced pharmaceutical intermediates and agrochemicals due to its unique trifluoromethyl and chloro substitution pattern. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in anti-inflammatory, antiviral, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, esterifications, and amide bond formations to introduce the phenylacetic acid moiety with halogen and fluorine functionality.
• Material Science Research: Utilized in the development of novel polymers and advanced organic materials with specific electronic or surface properties.

Basic Information

Product Name	5-Chloro-2-(Trifluoromethyl)Phenylacetic Acid
CAS No.	261763-25-1
Molecular Formula	C9H6ClF3O2
Molecular Weight	238.59 g/mol
Synonyms	2-(5-Chloro-2-(trifluoromethyl)phenyl)acetic acid; [5-Chloro-2-(trifluoromethyl)phenyl]acetic acid; 5-Chloro-α,α,α-trifluoro-o-toluic Acid (related); 5-Chloro-2-trifluoromethylphenylacetic Acid; 2-(5-Chloro-2-(trifluoromethyl)phenyl)ethanoic acid; 261763-25-1; 5-Chloro-2-(trifluoromethyl)benzeneacetic acid
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-(Trifluoromethyl)Phenylacetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its acidic nature, handle with appropriate personal protective equipment in a controlled environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.