Description

3-Chloro-2-Fluoro-5-(Trifluoromethyl)Phenylacetic Acid is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its value lies in its unique molecular scaffold, which combines halogen and trifluoromethyl substituents to impart specific electronic and steric properties to target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and chlorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and materials science.
• Fluorinated Compound Library Building: Essential for constructing diverse compound libraries in high-throughput screening for drug discovery.
• Chemical Research & Development: Employed in academic and industrial R&D settings for exploring new synthetic methodologies and reaction pathways involving fluorinated aromatics.

Basic Information

Product Name	3-Chloro-2-Fluoro-5-(Trifluoromethyl)Phenylacetic Acid
CAS No.	261763-13-7
Molecular Formula	C9H5ClF4O2
Molecular Weight	256.58 g/mol
Synonyms	2-(3-Chloro-2-fluoro-5-(trifluoromethyl)phenyl)acetic acid; [3-Chloro-2-fluoro-5-(trifluoromethyl)phenyl]acetic acid; 3-Chloro-2-fluoro-5-(trifluoromethyl)benzeneacetic acid; 261763-13-7; α-(3-Chloro-2-fluoro-5-(trifluoromethyl)phenyl)acetic acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Fluoro-5-(Trifluoromethyl)Phenylacetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. This material is moisture-sensitive (hygroscopic).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.