Description

3-Chloro-2-Fluorophenylacetic Acid is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its unique halogenated phenylacetic acid structure makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine and chlorine substituents can enhance biological activity and stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for specialty chemicals requiring specific halogenated phenylacetic acid motifs.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D in medicinal chemistry and material science for structure-activity relationship (SAR) studies.

Basic Information

Product Name	3-Chloro-2-Fluorophenylacetic Acid
CAS No.	261762-96-3
Molecular Formula	C8H6ClFO2
Molecular Weight	188.58 g/mol
Synonyms	(3-Chloro-2-fluorophenyl)acetic Acid; 2-(3-Chloro-2-fluorophenyl)acetic Acid; 3-Chloro-2-fluoro-benzeneacetic Acid; α-(3-Chloro-2-fluorophenyl)acetic Acid; 3-Chloro-2-fluorobenzeneacetic Acid; 2-Fluoro-3-chlorophenylacetic Acid; NSC 405124; 261762-96-3 (CAS)
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Fluorophenylacetic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided and traceable to each production lot, supporting compliance with cGMP and ISO 9001 standards for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of heat.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.