Description

2-Chloro-6-Fluoro-3-Methylphenylacetic Acid is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific halogenated structure enables precise molecular modifications. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-inflammatory agents.
• Agrochemical Synthesis: Serves as a key building block for developing advanced herbicides and pesticides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions, which are fundamental in modern organic synthesis.
• Material Science Research: Employed in the synthesis of functionalized monomers for advanced polymers and liquid crystals, where the chloro-fluoro substitution pattern imparts unique electronic properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex aromatic acids.

Basic Information

Product Name	2-Chloro-6-Fluoro-3-Methylphenylacetic Acid
CAS No.	261762-92-9
Molecular Formula	C9H8ClFO2
Molecular Weight	202.61 g/mol
Synonyms	(2-Chloro-6-fluoro-3-methylphenyl)acetic acid; 2-(2-Chloro-6-fluoro-3-methylphenyl)acetic acid; α-(2-Chloro-6-fluoro-m-tolyl)acetic acid; 2-Chloro-6-fluoro-3-methylbenzeneacetic acid; 261762-92-9; 2-Chloro-6-fluoro-3-methyl-benzenacetic acid; Acetic acid, (2-chloro-6-fluoro-3-methylphenyl)-
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Fluoro-3-Methylphenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical and agrochemical applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.