Description

6-Chloro-2-Fluoro-3-Methylanisole is a high-purity fluorinated anisole derivative, serving as a critical building block in advanced organic synthesis. Its unique halogen-substituted aromatic structure makes it an invaluable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine and chlorine substituents enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for high-performance displays.
• Organic Electronic Materials: Employed in the development of organic semiconductors and charge-transport materials due to its electron-withdrawing halogen groups.
• Chemical Research & Development: A versatile reagent for cross-coupling reactions, such as Suzuki and Buchwald-Hartwig amination, in academic and industrial R&D laboratories.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized halogenated dyes and pigments with improved lightfastness and color properties.

Basic Information

Product Name	6-Chloro-2-Fluoro-3-Methylanisole
CAS No.	261762-80-5
Molecular Formula	C8H8ClFO
Molecular Weight	174.60 g/mol
Synonyms	1-Chloro-4-fluoro-5-methoxy-2-methylbenzene; 2-Fluoro-6-chloro-3-methylanisole; 3-Methyl-6-chloro-2-fluoroanisole; Benzene, 1-chloro-4-fluoro-5-methoxy-2-methyl-; 2-Chloro-6-fluoro-3-methylanisole (isomer); 6-Chloro-2-fluoro-3-methoxy-1-methylbenzene; 4-Fluoro-5-methoxy-2-methyl-1-chlorobenzene
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-Fluoro-3-Methylanisole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We maintain full traceability and can support compliance with REACH, ISO, and cGMP standards as required for your application.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.