Description

2-Chloro-6-Fluoro-3-Methylanisole is a high-purity, multi-functional aromatic ether building block of significant importance in advanced organic synthesis. Its unique halogen-substituted anisole structure makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily needed by R&D and production chemists in the pharmaceutical and agrochemical industries, where it serves as a versatile precursor for active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the chloro and fluoro substituents enhance biological activity and environmental stability.
• Liquid Crystal & Electronic Chemicals: Serves as a precursor in the manufacture of fluorinated liquid crystal compounds and other specialty electronic materials for display technologies.
• Organic Synthesis & Research: A versatile reagent for Suzuki-Miyaura and other cross-coupling reactions, as well as for introducing methoxy and halogen functionalities into complex molecular architectures.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized halogenated dyes and pigments that require specific light-fastness and color properties.

Basic Information

Item	Details
Product Name	2-Chloro-6-Fluoro-3-Methylanisole
CAS No.	261762-79-2
Molecular Formula	C8H8ClFO
Molecular Weight	174.60 g/mol
Synonyms	1-Chloro-2-fluoro-3-methoxy-5-methylbenzene; 2-Chloro-6-fluoro-3-methoxytoluene; 3-Methoxy-2-chloro-6-fluorotoluene; 2-Chloro-6-fluoro-m-anisole; 2-Chloro-6-fluoro-3-methylphenyl methyl ether; Benzene, 1-chloro-2-fluoro-3-methoxy-5-methyl-; 2-Fluoro-6-chloro-3-methylanisole
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Fluoro-3-Methylanisole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, GC, and NMR to ensure identity, purity, and consistency meet the high standards required for pharmaceutical and agrochemical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, and we support customer audits and regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly closed and stored in a dry and inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.