Description

3-Chloro-2-Fluoroanisole is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its value lies in its role as a key intermediate for introducing specific halogenated methoxy motifs into complex molecular architectures. This compound is primarily needed by R&D and production chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the chloro-fluoro-anisole structure imparts specific biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated aromatic cores for electronic and display materials, enhancing thermal stability and electronic properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to create complex, functionalized arenes.
• Chemical Research & Development: Essential for academic and industrial R&D focused on exploring new fluorination methodologies and structure-activity relationships.

Basic Information

Product Name	3-Chloro-2-Fluoroanisole
CAS No.	261762-56-5
Molecular Formula	C7H6ClFO
Molecular Weight	160.57 g/mol
Synonyms	1-Chloro-2-fluoro-3-methoxybenzene; 2-Fluoro-3-chloroanisole; 3-Chloro-2-fluoromethoxybenzene; Benzene, 1-chloro-2-fluoro-3-methoxy-; 3-Chloro-2-fluoro-1-methoxybenzene; 2-Fluoro-3-chloro-1-methoxybenzene; 3-Chloro-2-fluoro phenyl methyl ether
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Fluoroanisole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with complete batch data are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and potential contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0% (Standard Grade)
Purity (GC/HPLC)	≥ 99.0% (High Purity Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.