Description

3-Chloro-2,6-Difluorophenylacetonitrile is a versatile and high-purity halogenated aromatic nitrile building block. This compound is critical for the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in molecules containing difluorophenyl and nitrile motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the chloro-difluoro substitution pattern confers specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of monomers or functional units for advanced polymers and liquid crystals.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical manufacturing.

Basic Information

Product Name	3-Chloro-2,6-Difluorophenylacetonitrile
CAS No.	261762-55-4
Molecular Formula	C8H4ClF2N
Molecular Weight	187.57 g/mol
Synonyms	2-(3-Chloro-2,6-difluorophenyl)acetonitrile; (3-Chloro-2,6-difluorophenyl)acetonitrile; 3-Chloro-2,6-difluorobenzeneacetonitrile; α-Chloro-2,6-difluorophenylacetonitrile (ambiguous); 261762-55-4; Benzeneacetonitrile, 3-chloro-2,6-difluoro-; Acetonitrile, (3-chloro-2,6-difluorophenyl)-
EINECS	Contact for details

Quality Control

Our 3-Chloro-2,6-Difluorophenylacetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.