Description

2-Chloro-3,6-Difluorophenylacetonitrile is a versatile and high-value fluorinated aromatic nitrile building block. This compound is critical for the synthesis of advanced agrochemicals and pharmaceuticals, where its unique halogenated structure enables precise molecular modifications. It is primarily sought after by research institutions and manufacturers in the fine chemical and life science sectors for developing novel active ingredients.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of modern herbicides, fungicides, and insecticides, leveraging the difluoro and chloro substituents for enhanced bioactivity and environmental stability.
• Pharmaceutical Building Block: Used in medicinal chemistry for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) with improved metabolic properties.
• Ligand and Catalyst Synthesis: Serves as a starting material for creating specialized ligands and catalysts used in cross-coupling and other transition metal-catalyzed reactions.
• Material Science Research: Employed in the development of advanced polymers and liquid crystals, where the fluorine atoms contribute to desired thermal and chemical resistance properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific fluorinated intermediates.

Basic Information

Product Name	2-Chloro-3,6-Difluorophenylacetonitrile
CAS No.	261762-54-3
Molecular Formula	C8H4ClF2N
Molecular Weight	187.57 g/mol
Synonyms	2-Chloro-3,6-difluorobenzyl cyanide; (2-Chloro-3,6-difluorophenyl)acetonitrile; 2-Chloro-3,6-difluorobenzeneacetonitrile; α-Chloro-3,6-difluorophenylacetonitrile; Benzeneacetonitrile, 2-chloro-3,6-difluoro-; 261762-54-3; 2,6-Difluoro-3-chlorophenylacetonitrile
EINECS	Contact for details

Quality Control

Our 2-Chloro-3,6-Difluorophenylacetonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.