Description

2-Chloro-3,6-Difluoroanisole is a versatile fluorinated anisole derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of halogen and methoxy substituents, which enable precise structural modifications in target molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the preparation of complex drug candidates, particularly in medicinal chemistry programs targeting CNS and anti-infective therapies.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the difluoro and chloro motifs contribute to biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated aromatic cores for electronic and display materials, enhancing charge transport and thermal properties.
• Organic Ligand Preparation: Utilized in creating specialized ligands for catalysis, where the electron-withdrawing halogens fine-tune metal complex reactivity.
• Chemical Research & Development: A valuable reagent for exploring new reaction pathways and constructing complex polyfunctional aromatic systems in academic and industrial R&D settings.

Basic Information

Product Name	2-Chloro-3,6-Difluoroanisole
CAS No.	261762-37-2
Molecular Formula	C7H5ClF2O
Molecular Weight	178.56 g/mol
Synonyms	1-Chloro-2,5-difluoro-3-methoxybenzene; 2-Chloro-3,6-difluorophenyl methyl ether; Benzene, 1-chloro-2,5-difluoro-3-methoxy-; 3-Methoxy-2,5-difluorochlorobenzene; 2,5-Difluoro-3-methoxychlorobenzene; 2-Chloro-3,6-difluoromethoxybenzene; 2-Chloro-1,4-difluoro-3-methoxybenzene
EINECS	Contact for details

Quality Control

Our 2-Chloro-3,6-Difluoroanisole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC/HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.